Chun Zhang Group

@Tianjin University

天津大学张淳课题组

 

 

 

张淳 教授 天津大学化学系

入选国家“青年千人计划”
入选天津市“青年千人计划”
入选天津大学“北洋学者计划”

办公室:天津大学北洋园校区51教531
e-mail: chunzhang@tju.edu.cn

 

本课题组常年招收硕士生和博士生,并招聘科研助理和博士后,欢迎联系和访问!

Research Interest:

# Discovery and development of new reaction for bio-active molecule synthesis

# Mechanistic studies of transition metal-catalyzed organic reactions

 


Education and Working Experience of Chun Zhang:

1. 2017/09 to today: Professor, Department of Chemistry, Tianjin University, Tianjin, China.

2. 2014/04 to 2017/08: Postdoctoral Research Fellow, Professor Matthew S. Sigman group, Department of Chemistry, University of Utah, Salt Lake City, Utah, USA.

3. 2013/08 to 2014/01: Research Assistant, Professor Ning Jiao group, College of Pharmacy, Peking University, Beijing, China.

4. 2008/09 to 2013/07: Ph. D. Candidate, Professor Ning Jiao group, College of Pharmacy, Peking University, Beijing, China.

5. 2004/09 to 2008/07: Undergraduate student, College of Pharmacy, China Pharmaceutical University, Nanjing, China.

 


Some selected publications:

1. Chun Zhang, Celine B. Santiago, Jennifer M. Crawford, Matthew S. Sigman*, Enantioselective Dehydrogenative Heck Arylations of Tri-substituted Alkenes with Indoles to Construct Quaternary Stereocenters, J. Am. Chem. Soc. 2015, 137, 15668.

2. Chun Zhang, Celine B. Santiago, Lei Kou, Matthew S. Sigman*, Alkenyl Carbonyl Derivatives in Enantioselective Redox Relay Heck Reactions: Accessing α,β-Unsaturated Systems, J. Am. Chem. Soc. 2015, 137, 7290.

3. Chun Zhang, Peng feng, Ning Jiao*, Cu-Catalyzed Esterification Reaction via Aerobic Oxygenation and C–C Bond Cleavage: An Approach to α-Ketoesters, J. Am. Chem. Soc. 2013, 135, 15257.

4. Chun Zhang, Ning Jiao*, Dioxygen activation under ambient conditions: Cu-catalyzed oxidative amidation−diketonization of terminal alkynes leading to α-ketoamides, J. Am. Chem. Soc. 2010, 132, 28.

5. Chun Zhang, Zejun Xu, Liangren Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative coupling of aryl acetaldehydes with anilines leading to α-ketoamides, Angew. Chem. Int. Ed. 2011, 50, 11088.

6. Chun Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative dehydrogenative coupling of anilines leading to aromatic azo compounds using dioxygen as an oxidant, Angew. Chem. Int. Ed. 2010, 49, 6174.

7. Zejun Xu,§ Chun Zhang,§ Ning Jiao*, (§ These authors contributed equally to this work) Copper-mediated aerobic oxidative dehydrogenative annulation of aldehydes, amines and molecular oxygen for oxazoles via C-H functionalization and dioxygen activation. Angew. Chem. Int. Ed. 2012, 51, 11367.

8. Chun Zhang, Brandon Tutkowski, Ryan J. DeLuca, Leo A. Joyce, Olaf Wiest, Matthew S. Sigman*, Palladium-catalyzed enantioselective Heck alkenylation of trisubstituted allylic alkenols: a redox-relay strategy to construct vicinal stereocenters, Chem. Sci. 2017, 8, 2277.

9. Chun Zhang, Conghui Tang, Ning Jiao*, Recent advances in copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process, Chem. Soc. Rev. 2012, 41, 3464.

10. Chun Zhang, Ning Jiao*, A Cu-catalyzed Practical Approach to α-Ketoesters under Air: an Efficient Aerobic Oxidative Dehydrogenative Coupling of Alcohols and α-Carbonyl Aldehydes, Org. Chem. Frontiers, 2014, 1, 109.

11. Chun Zhang, Liangren Zhang, Ning Jiao*, Catalyst and additive free procedure to construct benzimidazoles using air as the oxidant under room temperature. Green Chem. 2012, 14, 3273.

12. Chun Zhang, Xiaolin Zong, Liangren Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative cross-dehydrogenative coupling (CDC) of amine and α-carbonyl aldehyde: a pratical and efficient method to α-ketoamides with wide substrate scope. Org. Lett. 2012, 14, 3280.

13. Chun Zhang, Zejun Xu, Tao Shen, Guolin Wu, Liangren Zhang, Ning Jiao*, Mn-mediated aerobic oxidative C-C bond cleavage of aldehydes with dioxygen activation: a simple synthetic approach to formamide. Org. Lett. 2012, 14, 2362.

14. Chun Zhang, Liangren Zhang, Ning Jiao*, Multiple oxidative dehydrogenative functionalization of aryl acetaldehydes using molecular oxygen as oxidant leading to 2-oxo-acetamidines. Adv. Synth. Catal. 2012, 354, 1293.

15. Chun Zhang, Zejun Xu, Liangren Zhang, Ning Jiao*, Et3N-catalyzed dehydrogenative oxidation of α-unsubstituted carbonyl compounds with aryl diamine leading to quinoxalines using molecular oxygen as oxidant. Tetrahedron, 2012, 68, 5258.

16. Chun Zhang, Xiaoyang Wang, Ning Jiao*, Copper-Catalyzed Aerobic Oxidative C–C Bond Cleavage of 1,3-Diaryl­diketones To Synthesize 1,2-Diketones, Synlett, 2014, 25, 1458.