Chun Zhang Group

@Tianjin University





张淳 教授 天津大学化学系


cell phone:0086-15922186701



Research Interest:

# Discovery and development of new reaction for bio-active molecule synthesis

# Mechanistic studies of transition metal-catalyzed organic reactions


Education and Working Experience of Chun Zhang:

1. 2017/09 to today: Professor, Department of Chemistry, Tianjin University, Tianjin, China.

2. 2014/04 to 2017/08: Postdoctoral Research Fellow, Professor Matthew S. Sigman group, Department of Chemistry, University of Utah, Salt Lake City, Utah, USA.

3. 2013/08 to 2014/01: Research Assistant, Professor Ning Jiao group, College of Pharmacy, Peking University, Beijing, China.

4. 2008/09 to 2013/07: Ph. D. Candidate, Professor Ning Jiao group, College of Pharmacy, Peking University, Beijing, China.

5. 2004/09 to 2008/07: Undergraduate student, College of Pharmacy, China Pharmaceutical University, Nanjing, China.


Some selected publications:

1. Chun Zhang,  Brandon Tutkowski,  Ryan J. DeLuca,  Leo A. Joyce,  Olaf Wiest, Matthew S. Sigman*, Palladium-catalyzed enantioselective Heck alkenylation of trisubstituted allylic alkenols: a redox-relay strategy to construct vicinal stereocenters, Chem. Sci. 2017, 8, 2277.

2. Chun Zhang, Celine B. Santiago, Jennifer M. Crawford, Matthew S. Sigman*, Enantioselective Dehydrogenative Heck Arylations of Tri-substituted Alkenes with Indoles to Construct Quaternary Stereocenters, J. Am. Chem. Soc. 2015, 137, 15668.

3. Chun Zhang, Celine B. Santiago, Lei Kou, Matthew S. Sigman*, Alkenyl Carbonyl Derivatives in Enantioselective Redox Relay Heck Reactions: Accessing α,β-Unsaturated Systems, J. Am. Chem. Soc. 2015, 137, 7290.

4. Chun Zhang, Ning Jiao*, A Cu-catalyzed Practical Approach to α-Ketoesters under Air: an Efficient Aerobic Oxidative Dehydrogenative Coupling of Alcohols and α-Carbonyl Aldehydes, Org. Chem. Frontiers, 2014, 1, 109.

5. Chun Zhang, Xiaoyang Wang, Ning Jiao*, Copper-Catalyzed Aerobic Oxidative C–C Bond Cleavage of 1,3-Diaryl­diketones To Synthesize 1,2-Diketones, Synlett, 2014, 25, 1458.

6. Chun Zhang, Peng feng, Ning Jiao*, Cu-Catalyzed Esterification Reaction via Aerobic Oxygenation and C–C Bond Cleavage: An Approach to α-Ketoesters, J. Am. Chem. Soc. 2013, 135, 15257.

7. Chun Zhang, Liangren Zhang, Ning Jiao*, Catalyst and additive free procedure to construct benzimidazoles using air as the oxidant under room temperature. Green Chem. 2012, 14, 3273.

8. Chun Zhang, Conghui Tang, Ning Jiao*, Recent advances in copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process, Chem. Soc. Rev. 2012, 41, 3464.

9. Zejun Xu,§ Chun Zhang,§ Ning Jiao*, (§ These authors contributed equally to this work) Copper-mediated aerobic oxidative dehydrogenative annulation of aldehydes, amines and molecular oxygen for oxazoles via C-H functionalization and dioxygen activation. Angew. Chem. Int. Ed. 2012, 51, 11367.

10. Chun Zhang, Xiaolin Zong, Liangren Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative cross-dehydrogenative coupling (CDC) of amine and α-carbonyl aldehyde: a pratical and efficient method to α-ketoamides with wide substrate scope. Org. Lett. 2012, 14, 3280.

11. Chun Zhang, Zejun Xu, Tao Shen, Guolin Wu, Liangren Zhang, Ning Jiao*, Mn-mediated aerobic oxidative C-C bond cleavage of aldehydes with dioxygen activation: a simple synthetic approach to formamide. Org. Lett. 2012, 14, 2362.

12. Chun Zhang, Zejun Xu, Liangren Zhang, Ning Jiao*, Et3N-catalyzed dehydrogenative oxidation of α-unsubstituted carbonyl compounds with aryl diamine leading to quinoxalines using molecular oxygen as oxidant. Tetrahedron. 2012, 68, 5258.

13. Chun Zhang, Liangren Zhang, Ning Jiao*, Multiple oxidative dehydrogenative functionalization of aryl acetaldehydes using molecular oxygen as oxidant leading to 2-oxo-acetamidines. Adv. Synth. Catal. 2012, 354, 1293.

14. Chun Zhang, Zejun Xu, Liangren Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative coupling of aryl acetaldehydes with anilines leading to α-ketoamides, Angew. Chem. Int. Ed. 2011, 50, 11088. (VIP, Highlighted by cover picture and highlighted by ChemCatChem)

15. Chun Zhang, Ning Jiao*, Copper-catalyzed aerobic oxidative dehydrogenative coupling of anilines leading to aromatic azo compounds using dioxygen as an oxidant, Angew. Chem. Int. Ed. 2010, 49, 6174.

16. Chun Zhang, Ning Jiao*, Dioxygen activation under ambient conditions: Cu-catalyzed oxidative amidation−diketonization of terminal alkynes leading to α-ketoamides, J. Am. Chem. Soc. 2010, 132, 28.