黄文华

出生年月:19668

实验室:51543(北洋校区)

手机:13752506293

Email: huangwh@tju.edu.cn

学习和工作经历

20047月-现在, 天津大学化学系副教授,硕士导师。

20018月-20047, Research associate, Department of Chemistry & Chemical Biology and New York Center for Studies on the Origins of Life, Rensselaer Polytechnic Institute, Troy, USA.

19999月-20017, Research associate, Department of Chemistry, University of Illinois at Chicago, Chicago, USA.

19959月-199812月,毕业于中科院上海有机化学研究所并获理学博士学位。

19928月-19957月,毕业于中科院兰州化学物理研究所并获理学硕士学位。

198910月-19927, 在湖南省辰溪县耐火材料厂、县经委和县工业局任技术管理干部。

教学活动

现承担生物化学、有机化学和有机化学实验等课程的教学。至201512月已指导10名研究生毕业。

研究领域

主要研究方向是元素有机化学,包括有机磷化学和有机硼化学,致力于应用绿色化学和生物化学理念发展新的有机合成方法,应用于碳-碳键偶联、碳-碳双键的形成、小环化合物的合成以及有机小分子催化等方面,现承担国家自然科学基金面上项目一项(No. 2127217080万)。

发表论文

[1]. 荣红英,黄文华*。非经典Wittig反应的最新进展。《化学与生物工程》201532(10), doi: 10.3969/j.issn.1672-5425.2015.10.001.

[2]. Wenhua Huang* and Jie Xu. In situ generation of formaldehyde and triphenylphosphine from (hydroxymethyl)triphenylphosphonium and its application in Wittig olefination. Syn. Commun. 2015, 45, 1777-1782.

[3]. Wenhua Huang,* Hong-Ying Rong, and Jie Xu. Cyclic a-alkoxyphosphonium salts from (2-(diphenylphosphino)phenyl)methanol and aldehydes and their application in synthesis of vinyl ethers and ketones via Wittig olefination. J. Org. Chem. 2015, 80, 6628-6638.

[4]. Wenhua Huang,* Shuang-Hong Zhao and Ning Xu. Aryltriolborates as air- and water-stable bases for Wittig olefination. Synthesis 2015, 359-366.

[5]. Mei-Li Xu and Wenhua Huang*. Syntheses of 9-triptycylisothiocyanate, (10-amino-9-triptycyl)carboxylic acid and their derivatives. Synth. Commun. 2014, 44, 3435-3440.

[6]. Wenhua Huang,* Shuang-Hong Zhao and Guang-Ping Dong. Wittig olefination using phosphonium tetraphenylborate in the absence of additional base. Phosphorus, Sulfur, and Silicon and the Related Elements. 2014, 189, 1802-1810.

[7]. Mei-Li Xu and Wenhua Huang*. Metal-free carbon-carbon cross-couplings between the ion pairs in sulfonium tetraphenylborates. Tetrahedron Lett. 2014, 55, 4230-4232.

[8]. 沙文彬,黄文华。N-3-甲酰基苯基)甘氨酸衍生物的合成。化学试剂,20133511963-966.

[9]. 沙文彬,黄文华。硼化合物催化的直接酰胺化反应研究进展。化学与生物工程,201330611-16.

[10]. Wenhua Huang* and Wen-Bin Sha. Direct amide formation from N-arylglycine ethyl ester and carboxylic acids catalyzed by phenylboronic acid. J. Chem. Res. 2013, 460-463.

[11]. Wenhua Huang* and Lai-Ling Wang. One-pot synthesis of cyclopropane derivatives with a controlled cis:trans stereoselectivity by Wittig olefination-sulfur ylide cyclopropanation sequence. J. Chem. Res. 2013, 380-384.

[12]. Wenhua Huang* and Mei-Li Xu. Synthesis of imides and benzoylureas by direct oxidation of N-methylenes of amides and benzylureas. J. Chem. Res. 2013, 77-79.

[13]. Wenhua Huang,* Guangping Dong and Zumureti Mijiti. One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N0-diisopropylcarbodiimide and Wittig olefination. Tetrahedron 2012, 68, 977-981.

[14]. Hong Yue, Hongmei Zhang, Meiling Wang and Wenhua Huang*. Novel route to N-acyl-N’-formyl aminal. Syn. Commun. 2009, 39, 484-491.

[15]. Wenhua Huang,* Meiling Wang and Hong Yue. Conversion of N-acyl amino acids to imides via oxidative decarboxylation induced by Ag+/Cu2+/S2O82- in water. Synthesis 2008, 1342-1344.

[16]. Wenhua Huang,* Jingyi Li and Lihua Ou. A facile synthesis of isoquinolines, β-carbolines, and 3-deazapurines. Syn. Commun. 2007, 37, 2137-2143.

[17]. Wenhua Huang* and Li’e Zhang. A facile synthesis of N-formylbenzamides by oxidative decarboxylation of N-aroylglycine induced by Ag+/S2O82-. J. Chem. Res. (S) 2006, 738-739.

[18]. Wenhua Huang and James P. Ferris. One-step, regioselective synthesis of up to 50-mers of RNA oligomers by montmorillonite catalysis. J. Am. Chem. Soc. 2006, 128, 8914-8919

[19]. Michael F. Aldersley, James P. Ferris, Wenhua Huang, Prakash C. Joshi & Dmitri Zagorevski. Oligonucleotides from montmorillonite catalysis; Analysis and modeling. Origins of Life and Evolution of the Biosphere 2006, 36, 289-291.

[20]. James P. Ferris, Prakash C. Joshi, Kong-Jiang Wang, Shin Miyakawa and Wenhua Huang. Catalysis in prebiotic chemistry: application to RNA synthesis. Advances in Space Research 2004, 33, 100-105.

[21]. Wenhua Huang and James P. Ferris. Synthesis of 30-40 mers of RNAs from unblocked monomers. A simple approach to the RNA world. Chem. Comm. 2003, 1458-1459.

[22]. David Crich and Wenhua Huang. Dynamics of alkene radical cation/phosphate anion pair formation from nucleotide C4' radicals. The DNA/RNA paradox revisited. J. Am. Chem. Soc. 2001, 123, 9239-9245.

[23]. Wen-Hua Huang, Yao-Zeng Huang and Li-Xin Dai. Tellurium-zinc exchange between organotelluronium salts and diethylzinc-reaction of the in situ generated mixed diorganozinc with carbonyl compounds. Tetrahedron Lett. 1998, 39, 6953-6956.

[24]. 黄文华,潘光明。改良法合成两个含硅芳香二酸酐。化学试剂 1998, 20, 54-55.

 

学术交流

参加了中国化学会第27-29届学术年会,2015年还参加了第25届国际杂环化学大会,相关工作以口头报告的形式进行了交流。