照片

姓名: 聂晶
性别:
职称: 副教授

专业: 有机化学
单位: 化学系
电话:  022-27403475
EMAIL
:  niejing1121@126.com 
研究方向1:有机氟化学
研究方向2:不对称合成
研究简历:
2004/09
2009/07:天津大学理学院,博士,导师:马军安教授

2009/072012/12:天津大学理学院,讲师

2012/12至今:天津大学理学院,副教授

代表性论文与著作:

[1] Zhang Ke-Feng, Nie Jing, Guo Ran, Zheng Yan, Ma Jun-An*, Chiral Phosphoric Acid-Catalyzed Asymmetric Aza-Friedel-Crafts Reaction of Indoles with Cyclic N-Acylketimines: Enantioselective Synthesis of Trifluoromethyldihydroquinazolines, Adv. Synth. Catal. 355(17), 3497-3502, 2013.

[2] Li Feng, Nie Jing, Sun Long, Zheng Yan, Ma Jun-An*, Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles, Angew. Chem., Int. Ed. 52(24), 6255-6258, 2013.

[3] Yuan Hai-Na, Wang Shuai, Nie Jing, Meng Wei, Yao Qing-Wei, Ma Jun-An*, Hydrogen-Bond-Directed Enantioselective Decarboxylative Mannich Reaction of -Ketoacids with Ketimines: Application to the Synthesis of Anti-HIV Drug DPC083, Angew. Chem., Int. Ed. 52(14), 3869-3873, 2013.

[4] Wu Jun-Wei, Li Feng, Zheng Yan, Nie Jing*, DABCO-mediated one-pot sequential transformation:convenient access to fluorinated 1H-pyrazol-5(4H)-ones, Tetrahedron Lett. 53(36), 4828-4831, 2012.

[5] Liu Cui-Bo, Meng Wei, Li Feng, Wang Shuai, Nie Jing, Ma Jun-An*, A Facile Parallel Synthesis of Trifluoroethyl-Substituted Alkynes, Angew. Chem., Int. Ed. 51(25), 6227-6230, 2012.

[6] Nie Jing, Hua Ming-Qing, Xiong Heng-Ying, Zheng Yan, Ma Jun-An*, Asymmetric phase-transfer-catalyzed conjugate addition of glycine imine to exocyclic alfa, beta-unsatutrated ketones: construction of polycyclic imines containing three stereocenters, J. Org. Chem. 77(9), 4209-4216, 2012.

[7] Li Feng, Nie Jing, Wu Jun-Wei, Zheng Yan, Jun-An Ma*, Stereoselective synthesis of fluorinated 2,3-dihydroquinolin-4(1H)-ones via a one-pot multistep transformation, J. Org. Chem. 77(5), 2398-2406, 2012.

[8] Wang Lian, Meng Wei, Zhu Chuan-Le, Zheng Yan, Nie Jing, Ma Jun-An*, The long-arm effect: influence of axially chiral phosphoramidite ligands on the diastereo- and enantioselectivity of the tandem 1,4-addition/fluorination, Angew. Chem., Int. Ed. 50(40), 9442-9446, 2011.

[9] Nie Jing, Li Xiao-Juan, Zheng Dong-Hua, Zhang Fa-Guang, Cui Shumin, Jun-An Ma*, Chiral bifunctional thiourea-catalyzed enantioselective aldol reaction of trifluoroacetaldehyde hemiacetal with aromatic ketones, J. Fluorine Chem. 132(7), 468-473, 2011.

[10] Zhu Chuan-Le, Zhang Fa-Guang, Meng Wei, Nie Jing, Cahard Dominique, Ma Jun-An*, Enantioselective base-free electrophilic amination of benzofuran-2(3H)-ones: catalysis by binol-derived P-spiro quaternary phosphonium salts, Angew. Chem., Int. Ed. 50(26), 5869-5872, 2011.

[11] Zhang Guang-Wu, Meng Wei, Ma Hai, Nie Jing, Zhang Wen-Qin, Ma Jun-An*, Catalytic enantioselective alkynylation of trifluoromethyl ketones: pronounced metal fluoride effects and implications of zinc-to-titanium transmetallation, Angew. Chem., Int. Ed. 50(15), 3538-3542, 2011.

[12] Nie Jing, Guo Hong-Chao, Cahard Dominique, Ma Jun-An*, Asymmetric construction of stereogenic carbon centers featuring a trifluomethyl group from prochiral trifluoromethylated substrates, Chem. Rev. 111(2), 455-529, 2011.

[13] Nie Jing, Zhang Guang-Wu, Wang Lian, Zheng Dong-Hua, Zheng Yan, Ma Jun-An*, Chiral Brønsted Acid-Catalyzed Enantioselective Arylation of Ethyl Trifluoroacetoacetate and Ethyl Trifluoropyruvate, Eur. J. Org. Chem., 3145-3149. 2009

[14] Nie Jing, Zhang Guang-Wu, Wang Lian, Fu AiPing, Zheng Yan, Ma Jun-An*, A Perfect Double Role of CF3 Groups in Activating Substrates and Stabilizing Adducts: the Chiral Brønsted Acid-Catalyzed Direct Arylation of Trifluoromethyl Ketones, Chem. Commun., 2356-2358. 2009

[15] Nie Jing, Zhu Hong-Wei, Cui Han-Feng, Hua Ming-Qing, Ma Jun-An*, Catalytic Stereoselective Synthesis of Highly Substituted Indanones via Tandem Nazarov Cyclization and Electrophilic Flurination Trapping, Org. Lett., 9, 3053-3056. 2007

 主要论著:

1、   《仪器分析》,刘宇主编,天津大学出版社,2010

2、   《有机化学简明教程》,郑艳主编,高等教育出版社

 

荣誉和奖励:

1、   2011年,天津市优秀博士论文,催化立体选择性合成含氟有机化合物的反应研究

2、   2012年,被授予北洋学者-青年骨干教师称号

讲授主要课程:

1、   高等有机化学

2、   基础有机化学实验

3、   精细合成化学实验

正在承担项目: 
 1
、项目负责人:国家自然科学基金面上项目仿生启发下基于β-酮酸催化脱羧反应在有机合成中的应用拓展与深入85万,批准号:21472137 起止时间:20151201812

2、项目负责人:天津市科委青年基金项目新型手性亲电三氟甲基化试剂的设计合成及其应用6万,批准号:2014FQ-0028,起止时间:2014420173

已完成项目:

项目负责人:国家自然科学基金青年项目基于潜手性三氟甲基及其衍生物的催化不对称转化反应研究19万,批准号:21002068,起止时间:20111月至201312月,已结题。

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